Israel Reference Genome Study (IRGS)
Mapping Genetic Diversity in Israel
The Israel Reference Genome Study (IRGS) is a national initiative led by Psifas, aiming to better understand genetic variation across Israel’s diverse population groups. By sequencing the whole genome of 50 individuals from over 60 distinct subpopulations, the study captures a unique and detailed map of genetic diversity.
Mapping Israeli population’s diversity with unprecedented breadth and depth
Improves accuracy of medical genetic findings for under-represented populations in other biobanks
~ 60 Sub populations
50 individuals sampled for each sub population
Research partnership agreement funded by Illumina
High standard
WGS data
Graph genome representing all ethnic groups
Building a Population-Based
Reference Genome
A key component of the study is the construction of a population-based reference genome that reflects the mosaic of ancestries in Israel. The project also identifies ethnic-specific allele frequencies, helping researchers uncover disease-associated patterns and population-level risk factors.
High Standards Through Strategic Partnerships
Developed in partnership with Illumina, the study meets high standards of data quality and scientific integrity.
The genomic data can be integrated with broader clinical datasets, offering valuable insights for public health, genetics, and precision medicine.
Collaborate with Psifas
Psifas invites collaboration with institutions and researchers interested in leveraging this unique genomic resource.
To learn more about data access opportunities or to partner on related projects, contact us.